Top Spot Treatments
- Clinique Acne Solutions Spot Treatment
This spot treatment targets blemishes quickly with salicylic acid to reduce redness and inflammation. Its lightweight formula absorbs rapidly without drying the skin. Suitable for all skin types, it helps prevent future breakouts. Dermatologist tested for gentle yet effective action.
- La Roche-Posay Effaclar Duo+ Acne Treatment
Effaclar Duo+ combines micro-exfoliating LHA and salicylic acid to unclog pores and reduce blemishes. It also contains niacinamide to soothe irritation and prevent marks. The non-comedogenic formula helps clear existing acne while preventing new spots. Clinically proven to improve skin texture and clarity.
- Mario Badescu Drying Lotion
A cult-favorite spot treatment that dries out surface blemishes overnight. Contains salicylic acid, sulfur, and zinc oxide to absorb excess oil and reduce inflammation. The pink sediment settles at the bottom, so application is targeted and effective. Ideal for fast-acting relief on stubborn spots.
- Neutrogena On-The-Spot Acne Treatment
Formulated with 2.5% benzoyl peroxide for effective acne fighting without excess dryness. This fast-acting spot treatment penetrates pores to eliminate acne-causing bacteria. Its gentle formula is suitable for sensitive skin and can be used daily. Helps reduce size and redness of pimples quickly.
- Paula's Choice CLEAR Acne Spot Treatment
Contains 5% benzoyl peroxide to rapidly treat breakouts and prevent new blemishes. Lightweight and non-irritating, it absorbs quickly and calms redness. The treatment also helps fade post-acne marks with consistent use. Free of fragrances and parabens, making it ideal for sensitive skin.
- The Ordinary Salicylic Acid 2% Solution
This treatment offers a high concentration of salicylic acid to exfoliate inside the pores and reduce inflammation. It helps clear blemishes and prevent future breakouts by removing dead skin cells. Lightweight and water-based, it absorbs quickly without clogging pores. Suitable for oily and acne-prone skin.
- Murad Rapid Relief Acne Spot Treatment
Features 2% salicylic acid combined with botanical extracts to reduce redness and shrink pimples fast. It penetrates deep into pores to clear blockages and calm irritation. The gel formula dries quickly, allowing for easy application under makeup. Clinically shown to reduce breakouts overnight.
- Kate Somerville EradiKate Acne Treatment
A potent spot treatment with 2% sulfur to reduce blemishes and absorb excess oil. It also contains calming ingredients to soothe irritated skin. The lightweight cream dries quickly without flaking or peeling. Perfect for targeting stubborn pimples and preventing new breakouts.
- COSRX Acne Pimple Master Patch
Hydrocolloid patches that protect blemishes from bacteria and picking while speeding up healing. These transparent patches absorb impurities and reduce inflammation. Discreet and easy to wear under makeup or overnight. Ideal for treating pimples without drying or irritation.
- First Aid Beauty FAB Skin Lab Retinol Spot Treatment
Combines retinol with soothing ingredients to target acne blemishes and promote skin renewal. This treatment reduces the appearance of spots and prevents future breakouts. The gentle formula minimizes irritation while improving skin texture. Suitable for sensitive and acne-prone skin.
- Mario Badescu Buffering Lotion
A gentle spot treatment with salicylic acid and sulfur to reduce inflammation and prevent scarring. It dries out blemishes while calming redness and irritation. The lotion absorbs quickly and can be layered under moisturizers or makeup. Ideal for treating active breakouts and preventing new ones.
- Dr. Dennis Gross Skincare Alpha Beta Rapid Clear Treatment
This powerful spot treatment combines alpha and beta hydroxy acids to exfoliate dead skin cells and clear clogged pores. It quickly reduces the size and redness of pimples. The formula is suitable for all skin types and helps prevent recurring acne. Dermatologist developed for fast-acting results.
- Garnier SkinActive Clearly Brilliant Anti-Spot Serum
Formulated with vitamin C and salicylic acid to brighten skin and diminish dark spots caused by acne. The serum reduces redness and promotes a clearer complexion. Lightweight and fast absorbing, it can be used daily to improve skin tone. Suitable for sensitive skin prone to discoloration.
- Origins Super Spot Remover Blemish Treatment Gel
A natural acne spot treatment with salicylic acid derived from willow bark extract. It targets blemishes to reduce size and redness without over-drying. The gel soothes irritated skin and promotes faster healing. Free from harsh chemicals, it's ideal for sensitive skin types.
- Youth To The People Superberry Hydrate + Glow Dream Mask
While primarily a mask, this product contains antioxidants and anti-inflammatory ingredients that help reduce the appearance of acne spots overnight. It hydrates and calms the skin while promoting a radiant complexion. The formula is suitable for all skin types, providing gentle spot care benefits.
- Kate Somerville D-tox Daily Detoxifying Treatment
A daily spot treatment infused with sulfur and salicylic acid to clear blemishes and prevent future breakouts. It helps regulate oil production and exfoliates dead skin cells. The lightweight formula soothes irritation and redness. Ideal for combination and oily skin.
- CeraVe Acne Foaming Cream Cleanser
Though a cleanser, it contains benzoyl peroxide to treat and prevent acne while cleansing. It helps clear pores without disrupting the protective skin barrier. Enriched with ceramides and niacinamide, it soothes and restores skin moisture. Suitable for daily use on acne-prone skin.
- Herbivore Botanicals Blue Tansy Resurfacing Clarity Mask
This mask contains salicylic acid and blue tansy oil to exfoliate and calm acne-prone skin. It reduces the appearance of blemishes and redness while promoting clearer skin. The gentle formula is suitable for sensitive skin and helps improve texture. Offers a soothing and effective spot treatment.
- Sunday Riley U.F.O. Ultra-Clarifying Face Oil
An oil-based spot treatment with 1.5% salicylic acid and natural oils to clear congested pores and reduce acne. It balances oil production and soothes inflammation. Lightweight and non-greasy, it absorbs quickly to promote a clearer, smoother complexion. Safe for daily use on blemish-prone skin.
- Burt's Bees Natural Acne Solutions Spot Treatment
Made with 2% salicylic acid sourced from willow bark to naturally fight acne. The treatment reduces redness and size of pimples without harsh chemicals. It contains soothing ingredients like tea tree oil to calm irritated skin. Perfect for those seeking a natural approach to spot care.
- Ren Clean Skincare Clearcalm 3 Clarifying Clay Mask
A purifying clay mask that detoxifies skin and reduces blemishes. It contains zinc to regulate oil and willow bark to exfoliate. This mask calms redness and helps prevent future breakouts. Ideal for oily and combination skin needing gentle yet effective spot care.
- Kiehl's Breakout Control Targeted Acne Spot Treatment
This non-drying gel contains 2.5% benzoyl peroxide to eliminate acne-causing bacteria and reduce inflammation. It penetrates pores to clear stubborn spots quickly. The formula also helps prevent new blemishes from forming. Suitable for sensitive skin, it minimizes irritation while treating acne.
- The Inkey List Beta Hydroxy Acid (BHA) Acne Treatment
A budget-friendly spot treatment featuring salicylic acid to exfoliate and unclog pores. It helps reduce inflammation and clear blemishes without over-drying. The lightweight formula is gentle enough for daily use. Ideal for oily and acne-prone skin types.
- Acure Incredibly Clear Spot Treatment
Contains 2% salicylic acid and organic botanical extracts to target blemishes and calm skin. The formula reduces redness and helps speed healing of pimples. Free from parabens, sulfates, and synthetic fragrances. Perfect for those looking for a natural, effective spot treatment.
- Drunk Elephant TLC Sukari Babyfacial
An at-home exfoliating treatment with AHA/BHA blend to deeply cleanse pores and improve skin texture. It helps fade acne marks and reduce breakouts. The formulation includes soothing ingredients to minimize irritation. Use weekly for clearer, smoother skin.
- Paula's Choice CLEAR Daily Skin Clearing Treatment
Formulated with 2.5% benzoyl peroxide to eliminate acne bacteria and reduce blemishes. This lightweight lotion absorbs quickly without clogging pores. It calms inflammation and prevents future breakouts. Suitable for all skin types, including sensitive skin.
- Elemis Pro-Collagen Cleansing Balm
While primarily a cleanser, this balm contains anti-inflammatory ingredients that help soothe and calm acne-prone skin. It gently removes impurities without stripping moisture. Regular use can reduce redness and improve skin clarity. Suitable for sensitive and breakout-prone skin.
- Vichy Normaderm Phytosolution Double-Correction Daily Care
A daily moisturizer with salicylic acid and probiotics to treat acne and strengthen skin barrier. It reduces blemishes and controls oil production. The non-comedogenic formula hydrates without clogging pores. Suitable for sensitive, acne-prone skin.
- Murad Rapid Resurfacing Peel
An exfoliating peel with glycolic acid and salicylic acid to smooth skin and clear pores. It helps fade acne scars and reduce breakouts. The formula includes soothing ingredients to minimize irritation. Use weekly for a clearer, brighter complexion.
- Biossance Squalane + Zinc Acne Spot Treatment
Contains zinc PCA to regulate sebum and squalane to moisturize and soothe skin. This spot treatment reduces redness and size of pimples without drying. Its lightweight texture absorbs quickly and is gentle on sensitive skin. Free of parabens and sulfates.
- Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant
A cult-favorite exfoliant with salicylic acid to unclog pores and reduce acne. It smooths skin texture and diminishes redness and blemishes. Lightweight and gentle, it can be used daily to prevent new breakouts. Suitable for all skin types, especially oily and acne-prone.
- Cosmedica Pure 10% Azelaic Acid Serum
Azelaic acid helps reduce acne, fade dark spots, and calm redness. This serum targets blemishes and evens skin tone. The formula is gentle and suitable for sensitive skin. Can be used daily to improve overall skin clarity.
- Glossier Zit Stick Spot Treatment
A convenient pen-style treatment with 2% salicylic acid for targeted acne care. It reduces inflammation and shrinks pimples quickly. The transparent formula dries fast and is easy to apply on the go. Ideal for mild to moderate blemishes.
- PCA Skin BPO 5% Acne Spot Treatment
Contains 5% benzoyl peroxide to kill acne-causing bacteria and reduce breakouts. The fast-absorbing gel minimizes redness and swelling. It is formulated with soothing ingredients to reduce potential irritation. Suitable for moderate acne flare-ups.
- REN Clearcalm 3 Clarifying Clay Cleanser
While a cleanser, this product helps reduce blemishes with zinc and willow bark extract. It gently exfoliates and detoxifies skin. The creamy formula soothes irritation and controls oil. Ideal for daily use on acne-prone skin.
- Lush Tea Tree Water Toner
A refreshing toner formulated with tea tree oil to fight acne-causing bacteria. It cools and soothes inflamed skin while reducing blemishes. Alcohol-free and hydrating, it restores skin’s natural balance. Perfect as a spot treatment booster within skincare routine.
- Murad Rapid Age Spot and Pigment Lightening Serum
This serum targets dark spots and post-acne marks with hydroquinone and glycolic acid. It helps fade discoloration and improve skin tone. The formula also reduces redness associated with acne scars. Suitable for all skin types needing spot correction.
- BHA Blackhead Power Liquid by Cosrx
A leave-on exfoliant with salicylic acid to clear pores and prevent acne. It reduces blackheads and calms irritation. The lightweight, water-based formula is gentle for daily use. Helps maintain clear and smooth skin.
- Aveeno Clear Complexion Daily Moisturizer
Contains salicylic acid and soy to reduce blemishes and improve skin tone. This moisturizer hydrates while preventing breakouts. It evens out skin texture and reduces redness. Non-comedogenic and suitable for sensitive skin.
- Peter Thomas Roth Acne Spot and Area Treatment
A powerful spot treatment with 10% benzoyl peroxide to target stubborn pimples. It reduces inflammation and kills acne bacteria quickly. The gel formula dries fast without irritation. Ideal for severe acne flare-ups.
- Murad Outsmart Acne Clarifying Treatment
Contains 2% salicylic acid to clear acne and prevent future breakouts. It also includes niacinamide to reduce redness and improve skin barrier. The lightweight lotion absorbs quickly without clogging pores. Suitable for daily use.
- Kora Organics Blemish Clearing Serum
A natural serum with tea tree oil, salicylic acid, and witch hazel to fight acne. It calms inflammation and reduces blemish size. The formula supports skin healing and prevents scars. Ideal for sensitive, acne-prone skin.
- Dr. Jart+ Cicapair Tiger Grass Spot Treatment
Targets redness and irritation associated with acne using centella asiatica extract. This spot treatment soothes inflamed skin and supports healing. It helps reduce the appearance of blemishes and scars. Suitable for sensitive skin types.
- Neutrogena Rapid Clear Stubborn Acne Spot Gel
Contains 10% benzoyl peroxide for fast and effective acne treatment. It penetrates deep to clear stubborn pimples and reduce redness. The gel dries quickly and helps prevent scarring. Non-comedogenic and dermatologist tested.
- COSRX AC Collection Acne Patch
Hydrocolloid patches that protect pimples from bacteria and absorb impurities. They speed up healing by creating a moist environment. Transparent and discreet, they can be worn under makeup or overnight. Ideal for active acne care.
- Lancer The Method: Acne Treatment
A multi-action spot treatment with salicylic acid and retinol to clear blemishes and prevent new breakouts. It exfoliates dead skin cells and reduces inflammation. The formula also promotes skin renewal and improves texture. Suitable for all skin types.
- Bioré Charcoal Acne Clearing Cleanser
While a cleanser, it contains salicylic acid and charcoal to deeply clean pores and reduce acne. It removes excess oil and impurities without drying skin. The formula helps prevent future breakouts. Suitable for oily and acne-prone skin.
- Avalon Organics Clarifying Toner
An organic toner with salicylic acid and botanicals to clear acne and soothe skin. It reduces redness and prevents blemishes. Alcohol-free and gentle for daily use. Supports a clearer, balanced complexion.
